Medimatics and Mediware signed a contract for the development of MwPharm++, the next generation dose calculation and therapeutic drug monitoring (TDM) software. MwPharm is the number one TDM software package on the market today (Fuchs et al., Proost et al.). MwPharm++ will be designed as an Edsim++ plugin taking advantage of Edsim's advanced PKPD-modeling capabilities. The features of MwPharm++ can be described as any model, any target and any database. The system will be able to connect to all major databases for which ODBC drivers are available. Integration into hospital information systems will be achieved by means of Mirth Connect. MwPharm++ is expected to be released before June 2014.